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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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  • Other Drug-Food Interactions:
  • Cialis (tadalafil) can interact with certain foods and beverages, possibly altering the effectiveness of these medications. Here are the key drug-food interactions:
  • : Grapefruit can increase the levels of tadalafil by interfering with its metabolism.
  • What is Cialis?

    Cialis is a prescription-only oral medication used to treat erectile dysfunction (ED). The medication belongs to a group of drugs called phosphodiesterase 5 (PDE5) inhibitors. This medication works by increasing blood flow to the penis to help men get an erection.

    How Does Cialis Work?

    Cialis is an oral medication that belongs to a group of medications known as PDE5 inhibitors. It works by blocking the enzyme that breaks down cGMP, the chemical responsible for breaking down cyclic GMP, the molecule that is responsible for relaxing the smooth muscle cells in the penis. This relaxes the muscles that allow blood flow to reach the penis and help a man get an erection.

    Cialis helps to improve the ability to achieve an erection by increasing blood flow to the penis. This can be achieved using:

    1. Taking Cialis by mouth with a glass of water:

    2. Drinking a glass of water with Cialis:

    3.

    It is important to note that cialis should only be taken as prescribed by a healthcare provider. It is not recommended to take Cialis more than once in a day. It is also important to note that not all men with erectile dysfunction are suitable for Cialis. Cialis is available in different forms such as tablets and oral suspension, which are available for those who prefer to take them separately.

    How Long Does Cialis Take To Work?

    Cialis takes about 30 minutes to work in approximately 5-10 minutes. This is because tadalafil is the only PDE5 inhibitor that works within this time frame.

    Cialis Super Active Plus

    is a high-strength, fast-acting, tadalafil-based drug containing Tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is available in tablet form and contains 5mg of Tadalafil per tablet.

    How does it work?

    Cialis Super Active Plus combines Tadalafil with vardenafil. Vardenafil works by increasing blood flow to the penis, which leads to a firm and lasting erection. Cialis Super Active Plus is a treatment for ED. It is available in the form of a tablet.

    How long does it take for Cialis Super Active Plus to work?

    The effects of Cialis Super Active Plus can last up to 36 hours, giving you a longer window of opportunity for sexual activity. It takes about 30 minutes for Cialis Super Active Plus to start working, but it is still possible to take it on an empty stomach. The effects are more pronounced after an hour of consumption.

    The dosage and duration of Cialis Super Active Plus is determined by the severity of erectile dysfunction, as well as the patient’s overall health. It is typically taken as needed before sexual activity.

    Is Cialis Super Active Plus safe for everyone?

    It is generally safe to use Cialis Super Active Plus for most people with erectile dysfunction. However, it is essential to consult your healthcare provider before use, especially if you have any pre-existing health conditions or are taking other medications.

    Additionally, Cialis Super Active Plus is generally well-tolerated by most users, but if you are taking a specific medication, your doctor will likely not prescribe it. Your doctor can assess your health and determine if Cialis Super Active Plus is right for you.

    Cialis Super Active Plus should only be used under the guidance of a healthcare professional. It is not recommended for use by children or individuals under the age of 18 years. Cialis Super Active Plus should not be used by people under the age of 18 years.

    Side effects of Cialis Super Active Plus

    Like all medications, Cialis Super Active Plus can cause side effects. However, they are generally mild and temporary. Common side effects include:

    • Flushing
    • Headache
    • Dizziness
    • Stuffy nose
    • Back pain

    In rare cases, more serious side effects like allergic reactions or vision changes can occur. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

    Inform your doctor about any other medications you are taking. Pregnant or breastfeeding women should consult their doctor before starting Cialis Super Active Plus.

    Cialis Super Active Plus precautions

    • If you are allergic to Tadalafil or its ingredients, you should not take Cialis Super Active Plus.
    • Cialis Super Active Plus can interact with certain medications, including certain drugs used to treat erectile dysfunction, such as nitrates and alpha-blockers. Inform your doctor about all the medications you are taking and any allergies you have.
    • Cialis Super Active Plus should not be used by children or individuals under the age of 18 years.
    • Cialis Super Active Plus is not recommended for use by individuals with a history of heart disease, high blood pressure, or liver or kidney problems.
    • If you have a history of liver or kidney problems, Cialis Super Active Plus may not be suitable for you.
    • If you are taking Cialis Super Active Plus for erectile dysfunction, it is recommended to avoid alcohol and grapefruit juice while taking it. It can lead to more severe side effects and interact with other medications.
    • Cialis Super Active Plus should not be used by people with a history of heart disease, high blood pressure, or liver or kidney problems.

    Tadalafil vs Vardenafil

    Cialis Super Active Plus contains Tadalafil and Vardenafil. The active ingredient is Tadalafil. Tadalafil is available in tablets.

    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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    In addition to the aforementioned, you should know that this medication can cause another side effect, called serotonin syndrome, if you take it with other medications you are taking regularly, such as certain antacids, calcium supplements, or antihypertensive medications.

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    In the US, 7 of 10 people taking Cialis-style medications for hair loss developed the condition upon taking them twice a day.

    Including Cialis-style medications for hair loss in the US in 2013. In the US in 2015, 5 of 10 people on Cialis-style medications developed the condition. In the US in 2016, 2 of 5 people on Cialis-style medications developed the condition. Cialis-style medications can increase your risk of serotonin syndrome.

    Although not regularly using Cialis, you should know that it may occasionally be taken as needed. However, like all medications, it can cause side effects. The following are some of the most common side effects of Cialis:

    • Diarrhea
    • Swelling in the arms and legs
    • Decreased sexual ability

    If you experience any new or worsening symptoms of depression, anxiety, role conditions, or any other mental health condition, seek medical attention immediately. This medication can cause a range of side effects, including dizziness, headache, or nervousness.

    Depression, anxiety, or other mental health conditions can sometimes impact your ability to think, think long term, and support yourself. Your doctor may need to adjust your dosage or recommend other treatment options to reduce your risk of developing depression, anxiety, or other mental health conditions.

    Some conditions can make taking Cialis more likely.

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    Cialis Tadalafil (20mg) 4 Tablets

    This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.

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    Grapefruit juice is available with this product.